Motif ID: NFY{A,B,C}.p2

Z-value: 3.664


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_412045090.865.5e-03Click!
NFYAchr6_+_410406870.865.9e-03Click!
NFYBchr12_-_1045318750.512.0e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_2263706 5.412 NM_006454
 MXD4
MAX dimerization protein 4
chr4_-_2263808 5.210 MXD4
MAX dimerization protein 4
chr6_-_167040700 5.128 NM_021135
 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167040506 4.815 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167040659 4.759 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_145438437 3.590 NM_006472
 TXNIP
thioredoxin interacting protein
chr1_+_221052845 3.249 HLX
H2.0-like homeobox
chr1_+_221052735 3.213 NM_021958
 HLX
H2.0-like homeobox
chr1_-_46598250 3.078 NM_003629
NM_001114172
 PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr14_-_74551073 3.014 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_-_182360889 2.942 GLUL
glutamate-ammonia ligase
chr14_-_52535765 2.831 NID2
nidogen 2 (osteonidogen)
chr1_-_150602047 2.806 ENSA
endosulfine alpha
chr7_+_94024201 2.768 COL1A2
collagen, type I, alpha 2
chr14_-_74551159 2.673 NM_005589
 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_-_52535711 2.623 NID2
nidogen 2 (osteonidogen)
chr1_+_163038934 2.568 NM_001113381
 RGS4
regulator of G-protein signaling 4
chr12_-_6665220 2.530 NM_001039670
NM_001193457
NM_080730
 IFFO1


intermediate filament family orphan 1


chr17_+_6347733 2.454 NM_001195228
NM_019013
 FAM64A

family with sequence similarity 64, member A

chr8_+_97506020 2.437 SDC2
syndecan 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 91 entries
enrichment   p-value GO term description
8.23 5.23e-03 GO:0002566 somatic diversification of immune receptors via somatic mutation
8.23 5.23e-03 GO:0016446 somatic hypermutation of immunoglobulin genes
5.29 1.09e-02 GO:0006298 mismatch repair
4.65 1.71e-02 GO:0002200 somatic diversification of immune receptors
4.63 1.01e-03 GO:0006695 cholesterol biosynthetic process
4.17 1.96e-03 GO:0016126 sterol biosynthetic process
4.14 5.49e-11 GO:0006334 nucleosome assembly
4.09 1.39e-12 GO:0065004 protein-DNA complex assembly
3.97 2.25e-12 GO:0071824 protein-DNA complex subunit organization
3.93 3.71e-10 GO:0031497 chromatin assembly
3.84 3.91e-10 GO:0034728 nucleosome organization
3.72 4.80e-02 GO:0051318 G1 phase
3.60 6.80e-12 GO:0006333 chromatin assembly or disassembly
3.16 1.55e-07 GO:0006323 DNA packaging
3.00 1.03e-07 GO:0071103 DNA conformation change
2.91 1.33e-04 GO:0007126 meiosis
2.91 1.33e-04 GO:0051327 M phase of meiotic cell cycle
2.88 1.66e-04 GO:0051321 meiotic cell cycle
2.74 5.65e-05 GO:0006310 DNA recombination
2.57 1.32e-02 GO:0000086 G2/M transition of mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
6.17 1.55e-02 GO:0032300 mismatch repair complex
4.23 1.22e-07 GO:0000786 nucleosome
3.23 2.98e-06 GO:0032993 protein-DNA complex
2.90 1.52e-12 GO:0000785 chromatin
2.71 7.72e-03 GO:0000790 nuclear chromatin
2.55 6.13e-06 GO:0044454 nuclear chromosome part
2.43 4.89e-15 GO:0044427 chromosomal part
2.36 1.39e-16 GO:0005694 chromosome
2.32 2.00e-05 GO:0000228 nuclear chromosome
2.23 9.00e-03 GO:0000775 chromosome, centromeric region
2.21 1.57e-02 GO:0000793 condensed chromosome
2.01 2.68e-02 GO:0005819 spindle
1.80 1.38e-04 GO:0005740 mitochondrial envelope
1.78 8.44e-07 GO:0044429 mitochondrial part
1.76 8.61e-04 GO:0031966 mitochondrial membrane
1.73 6.77e-06 GO:0015630 microtubule cytoskeleton
1.57 9.89e-08 GO:0005654 nucleoplasm
1.54 4.86e-03 GO:0031967 organelle envelope
1.52 1.11e-11 GO:0044428 nuclear part
1.52 1.17e-09 GO:0031981 nuclear lumen

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
9.06 3.02e-03 GO:0032404 mismatch repair complex binding
6.04 7.41e-03 GO:0030983 mismatched DNA binding
2.97 3.38e-02 GO:0003697 single-stranded DNA binding
1.69 3.34e-02 GO:0003712 transcription cofactor activity
1.68 3.62e-02 GO:0000988 protein binding transcription factor activity
1.68 3.62e-02 GO:0000989 transcription factor binding transcription factor activity
1.60 3.74e-04 GO:0019899 enzyme binding
1.52 1.06e-12 GO:0003677 DNA binding
1.50 4.98e-04 GO:0030528 transcription regulator activity
1.48 1.63e-03 GO:0001071 nucleic acid binding transcription factor activity
1.48 1.63e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.41 1.30e-12 GO:0003676 nucleic acid binding
1.27 2.29e-02 GO:0008270 zinc ion binding
1.26 1.47e-02 GO:0046914 transition metal ion binding
1.19 2.59e-08 GO:0005515 protein binding
1.13 1.36e-13 GO:0005488 binding